fig7

Figure 7. Regulatory DEL-DEmi-DEG network and relationships among DEmis, DELs and DEGs. (A) Regulatory network of DEL-DEmi-DEG pairs in pig SPEVs. The outer circle represents the important pathways related to sperm motility. The middle circle represents the six coexpression modules depicted in different colors. The inner circle displays the 12 upregulated miRNAs (red) and six down regulated miRNAs (green) in the L group. The hub DELs and DEGs are indicated by triangles and circles, respectively. The links show the DEL-DEmi regulatory relationships, DEmi-DEG regulatory relationships and DEG-pathway annotations. (B) Heatmap demonstratingthe hub DEGs annotatedin important pathways. (green: downregulated in the L group, red: upregulated in the L group). (C) DEL-DEmi-DEG interaction network of the turquoise module. (D) DEL-DEmi-DEG interaction network of the blue module.