Guest Editor(s)
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- Vincenza Dolo
Professor, Department of Life Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
Website | E-mail
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- Ilaria Giusti
Associate Professor, Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
Website | E-mail
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- Giuseppina Poppa
Professor, Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
Website | E-mail
Special Issue Introduction
The shedding of membrane vesicles into the extracellular space is a widespread phenomenon in normal cells and, more frequently, in tumor cells.
Growing evidence shows that Extracellular Vesicles (EVs) play a key role in multiple physiological and pathological processes as an important mechanism for intercellular communication, allowing cells to exchange proteins, lipids, and genetic material. The knowledge of the cellular processes modulating EVs biogenesis and cargo is essential to shedding light on their physiological and pathological functions.
The cell plasma membrane plays an important role in the shedding vesicles phenomenon, as the dynamics of the cell plasma membrane modulate their release. Even if much is demonstrated about the EVs cargo, much remains unknown, from a morphological point of view, regarding their origin, secretion, and fate once they reach the target cells.
We welcome submissions of Original Research and Review articles focusing on the morphological aspects during the release of the EVs from the cells or their interaction with target cells, using any high-resolution imaging techniques.
Submission Deadline
30 Jun 2023